The laboratory of Curtis Hughey in the Division of Molecular Medicine, Department of Medicine aims to understand the metabolic factors underlying the development of non-alcoholic fatty liver disease and the transition to liver cancer. The Hughey Lab is seeking a researcher who is enthusiastic to help in this research aim.
The Division of Molecular Medicine is a research-oriented division within the Department of Medicine. Faculty members utilize physiological and molecular approaches to better understand and improve the health of individuals and communities. A particular focus of the division is the use of genetically-engineered mouse models to investigate human metabolic diseases.
Job Duties/Responsibilities 30% - Mouse Phenotyping Prepare for metabolic studies in mice which includes fasting mice, preparing reagents, and setting up equipment Perform metabolic studies which includes handling mice, blood sampling and pipetting, and venous infusions Record and organize experimental data Harvest tissues from mice and store samples appropriately
30% - Coordination and Completion of Laboratory Experiments Assist with the design, validation, and implementation of procedures for new and existing laboratory assays Perform biochemical and molecular analyses on mouse plasma and tissues including qPCR, western blotting, and enzymatic assays
30% - Data Analysis and Presentation Use MATLAB-based software to build network reaction models to study metabolism Use statistical software to analyze data from experiments Assist in data organization and manuscript preparation.
10% - General Laboratory Administration and Support Purchase appropriate laboratory supplies and equipment Complete routine laboratory tasks including hazardous/chemical waste removal, washing of plastic and glassware, and equipment maintenance Assist in completing and maintaining regulatory documents Assist the PI in training new and existing lab members in lab procedures and protocols
All required qualifications must be documented on application materials.
Required Qualifications BS in science or a combination of education and work experience equal to four years Applies knowledge and skill to a recurring task or activity with emphasis typically on precision and timeliness of execution Demonstrated experience with metabolic research
Preferred Qualifications Demonstrated proficiency with MATLAB Past research experience in a wet lab
Internal Number: 330632
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