The Division of Molecular Medicine is a research-oriented division within the Department of Medicine. Faculty members utilize physiological and molecular approaches to better understand and improve the health of individuals and communities. A particular focus of the division is the use of genetically-engineered mouse models to investigate human metabolic diseases.
The laboratory of Curtis Hughey in the Division of Molecular Medicine, Department of Medicine aims to understand the metabolic factors underlying the development of non-alcoholic fatty liver disease and the transition to liver cancer. The Hughey Lab is seeking a researcher who is enthusiastic to help in this research aim.
Job Duties/Responsibilities 40% - Mouse Surgery ? Prepare reagents and equipment prior to mouse surgeries ? Perform vascular catheterization procedures in mice with aseptic surgical techniques ? Complete post-operative care for mice ? Ensure surgical tools and equipment are maintained in working order
30% - Mouse Husbandry and Colony Maintenance ? Manage multiple genetically-engineered mouse lines which includes setting up breeders, weaning mice, changing diets, monitoring health of the colony, and genotyping ? Assist with IACUC protocol generation, amendments, and compliance
15% - Mouse Phenotyping ? Prepare for metabolic studies in mice which includes fasting mice, preparing reagents, and setting up equipment ? Perform metabolic studies which includes handling mice, blood sampling and pipetting, and venous infusions ? Record and organize experimental data ? Harvest tissues from mice and store samples appropriately
15% - General Laboratory Administration/Support ? Purchase appropriate laboratory supplies and equipment ? Complete routine laboratory tasks including hazardous/chemical waste removal, washing of plastic and glassware, and equipment maintenance ? Assist in completing and maintaining regulatory documents ? Assist the PI in training undergraduate students, graduate students, and/or post-doctoral fellows
All required qualifications must be documented on application materials.
Required Qualifications ? BA/BS in science or a combination of education and related work experience equal to four years ? Willingness to harvest tissues from mouse models of disease ? Willingness to learn mouse vascular catheterization surgeries
Preferred Qualifications ? Documented experience in husbandry of genetically-engineered mice ? Demonstrated experience with performing mouse surgical procedures ? Demonstrated experience in genotyping and biochemical assays
Internal Number: 329523
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.